After prescribes the test compound screening manner of the central nervous system operation glaze and

摘要

PROBLEM TO BE SOLVED: To provide a screening method of a medicine acting on the central nervous system in which a compound to be tested is administered to a mammal abnormal in the immune system, and the concentration of the interleukin 6 in the blood of the mammal, and a method for evaluating the status under stress. ;SOLUTION: Medicines acting on the central nervous system can be extensively and easily screened, novel medicines acting on the central nervous system can be developed, and the medicines having the central action as the side effect can be screened, and the state under stress of the mammal abnormal in the immune system can be evaluated.;COPYRIGHT: (C)2001,JPO