Induction of tumor immunity by a variant of folate-binding protein

摘要

The present invention is directed to variants of antigens comprising folate binding protein epitope (E39) as a composition associated with providing immunity against a tumor in an individual. The variant is effective in inducing cytotoxic T-lymphocytes but preferably not to the extent that they become sensitive to silencing by elimination, such as by apoptosis, or by anergy, as in unresponsiveness.