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Method for producing gelatin with reduced endotoxin content and low endotoxin gelatin
Method for producing gelatin with reduced endotoxin content and low endotoxin gelatin
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机译:降低内毒素含量和低内毒素明胶的明胶的生产方法
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摘要
A method of manufacturing gelatin with reduced endotoxin content. The method comprises processing a starting material gelatin-containing solution containing gelatin and an endotoxin with an ultrafiltration film having a molecular weight cut-off falling within a range of from 20,000 to 300,000 and having a molecular weight cut-off capable of passing at least a portion of the gelatin contained in the starting material gelatin-containing solution to obtain a permeate that is a gelatin-containing solution with a reduced endotoxin content. A gelatin having an average molecular weight falling within a range of 1,000 to 300,000 and an endotoxin content of less than 1 EU/mL per 1.0 percent of protein.
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机译:一种制造具有降低的内毒素含量的明胶的方法。该方法包括用超滤膜处理含有明胶和内毒素的含明胶的原料溶液,所述超滤膜的分子量截断值在20,000至300,000的范围内,并且其分子量截断值至少能够通过原料含明胶的溶液中所含明胶的一部分,得到的渗透物是内毒素含量降低的含明胶的溶液。明胶的平均分子量在1,000到300,000的范围内,并且每1.0%的蛋白质内毒素含量小于1 EU / mL。
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