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Compositions for cultivation and induction of in vitro embryonic stem with germline transmission ability of (ES) cells
Compositions for cultivation and induction of in vitro embryonic stem with germline transmission ability of (ES) cells
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机译:具有(ES)细胞种系传递能力的体外胚胎干的培养和诱导组合物
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摘要
The present invention encompasses compositions for deriving, maintaining, and growing pluripotent and germ-line competent mammalian embryonic stem cells, and for deriving, maintaining, and growing adult human stem cells and/or adult early progenitor cells. Such compositions comprising a conditioned medium of a cell line expressing limited amounts of Leukemia Inhibitory Factor (LIF). The media of the present invention are used or for the generation of pluripotent and germ-line competent embryonic stem cells of mammals, and for the generation of adult human stem cells and/or adult early progenitor cells.
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