Use of interleukin 1 receptor antagonist and / or pyrrolidine dithiocarbamate for treating or preventing type II diabetes

摘要

Substances that inhibit the action of the members of the IL-1beta/NF-kappaB pathway can be used for protecting and preserving beta-cell mass and function in prediabetic and diabetic type 2 patients. Specifically, the present invention relates to the use of an Interleukin 1 receptor antagonist (IL-1Ra) and/or pyrrolidinedithiocarbamate (PDTC) for the treatment or prophylaxis of type 2 diabetes, as well as a method for the treatment of type 2 diabetes.