Detection, Prevention and Treatment of Infections in Implantable Devices

摘要

At least one embodiment is directed to a system (400) to detect a presence of bacteria or other infecting organism in proximity to an implanted device. The system (400) comprises one or more biological sensors (412, 414, 416, 418) a processing unit (420), and a screen (422). Biological sensors (412, 414, 416, 418) detect a presence of bacteria or infecting organisms. Once an infection is detected, the system (400) can activate the release of anti-infective elements local to the implanted device. In one embodiment, nanostructures are used to retain the anti-infective elements until needed. A pulsed electrical field is applied in infected regions proximal to the implanted device. The pulsed electric field initiates electroporation allowing increased cell wall penetration of the anti-infective elements. The system (400) responds to an infection after surgical implantation and eradicates bacteria without the need for surgical intervention or implant removal.