3-SUBSTITUTED-1H-INDOLE, 3-SUBSTITUTED-1H-PYRROLO2,3-BPYRIDINE AND 3-SUBSTITUTED-1H-PYRROLO3,2-BPYRIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES

摘要

The invention relates to 3-substituted-1H-indole, 3-substituted-1H-pyrrolo[2,3-b]pyridine, and 3-substituted-1H-pyrrolo[3,2-b]pyridine compounds of the Formula 1:; ;or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein, compositions comprising the compounds, and methods for making and using the compounds.