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METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS ACTIVE METABOLITES ISOLATED FROM LAURUS NOBILIS AND COMBINATIONS THEREOF

机译：耐月桂劳分离的耐甲氧西林金黄色葡萄球菌活性代谢产物及其组合

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摘要

This present provides kaempferol-3-(2-E,3-Z-di-p-coumaroyl)-rhamnoside, kaempferol-3-(2-Z-3-E-di-p-coumaroyl)-rhamnoside, and kaempferol-3-(2,3-di-Z-p-coumaroyl)-rhamnoside compounds useful as a new class of anti-bacterial agents. These compounds are extracted from Platanus occidentalis or Laurus nobilis. These compounds were found to exhibit anti-bacterial activity against methicillin resistant Staphylococcus aureus (MRSA).

机译：该礼物提供了kaempferol-3-（2-E，3-Z-di-p-香豆酰基）鼠李糖苷，kaempferol-3-（2-Z-3-E-di-p-香豆酰基）-鼠李糖苷和kaempferol- 3-（2,3-二-Zp-香豆酰基）-鼠李糖苷化合物可用作一类新型的抗菌剂。这些化合物是从 Platanus occidentalis 或 Laurus nobilis 提取的。发现这些化合物对耐甲氧西林的金黄色葡萄球菌（MRSA）具有抗菌活性。 展开▼

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公开/公告号US2010273726A1

专利类型

公开/公告日2010-10-28

原文格式PDF

申请/专利权人 MARK T. HAMANN;MOHAMED A. IBRAHIM;
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申请/专利号US20100767944

发明设计人 MARK T. HAMANN;MOHAMED A. IBRAHIM;
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申请日2010-04-27

分类号A61K31/7048;C07H17/04;A61P31/04;

国家 US

入库时间 2022-08-21 18:55:11

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机译：组成;药物组合物;联合疗法医疗器械至少一种缩水甘油环素和至少一种肝素的给药方法;甘氨酰环素和肝素的给药方法;治疗由革兰氏阴性和革兰氏阳性病原体，厌氧和耐甲氧西林的菌株以及对金黄色葡萄球菌有抵抗力的菌株（mssa和mrsa）引起的合并症（ciai）和腹腔内感染的并发症（ciai）和皮肤感染以及皮肤结构并发症（csssi）;革兰氏阴性和革兰氏阳性病原体，金黄色葡萄球菌厌氧和耐甲氧西林菌株（mssa和mrsa）引起的并发症（CIAI）和皮肤感染和皮肤复杂结构（CSSS）感染的腹腔内感染的治疗方法;抗生素给药方法;制品;套件式I的糖基西林或其药学上可接受的盐的用途;肝素或相的使用

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