首页> 外国专利> Peptide Derived From Prostate-Related Protein As Cancer Vaccine Candidate For Prostate Cancer Patient Who Is Positive For Hla-A3 Super-Type Allele Molecule

Peptide Derived From Prostate-Related Protein As Cancer Vaccine Candidate For Prostate Cancer Patient Who Is Positive For Hla-A3 Super-Type Allele Molecule

机译:前列腺相关蛋白衍生的肽作为Hla-A3超型等位基因分子阳性的前列腺癌患者的癌症疫苗候选者

摘要

According to the present invention, a peptide, which is a prostate-related protein derived peptide, capable of binding to an HLA-A3 supertype allele and recognized by the cellular and/or humoral immune system is provided. The peptides of the present invention make feasible the peptide-based anti-cancer vaccine therapy for prostate cancer patients with HLA-A3 supertype allele and useful for the treatment of prostate cancer patients with alleles other than HLA-A2 and -A24 to which cancer vaccine peptide candidates had been identified.
机译:根据本发明,提供了一种肽,其是前列腺相关蛋白衍生的肽,其能够与HLA-A3超型等位基因结合并被细胞和/或体液免疫系统识别。本发明的肽使得用于具有HLA-A3超型等位基因的前列腺癌患者的基于肽的抗癌疫苗疗法可行,并且对于治疗具有不同于HLA-A2和-A24等位基因的前列腺癌患者是有用的。肽候选物已被鉴定。

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