首页> 外国专利> COMPOSITION AND METHOD FOR TREAMENT OF INFLAMATION AND INFECTIONS OF THE OUTER EAR CANAL, NOSE AND PARANASAL SINUSES

COMPOSITION AND METHOD FOR TREAMENT OF INFLAMATION AND INFECTIONS OF THE OUTER EAR CANAL, NOSE AND PARANASAL SINUSES

机译:治疗外耳道,鼻和鼻窦炎症和感染的组合物和方法

摘要

A composition for topical application to the human external ear canal and nasal membranes for relief from symptoms of inflamation and infections and prophylaxis of sexually transmitted diseases the incoporates L-Ascorbic acid in a concentration of about 2% to about 25% wt/vol., within an acidic range or pH level of about 4.0 to 2.0 pH respectively, in an aqueous solution with a pharmaceutically acceptable liquid carrier. The liquid carrier in alternative exemplary embodiments is pure distilled water or normal 0.9% physiologic saline, pH adjusted in a pre determined composition for the desired therapeutic effect. The liquid carrier in alternative exemplary embodiments is pure distilled water or normal 0.9% physiologic saline, depending upon the preferred degree of absorption and bioavailability to the host tissues of the active ingredients in the novel invention. This may include sodium chloride as the preferred Sea Salt—which by analysis contains 99% sodium chloride and calcium, magnesium, sulphate, iron, and copper minerals. Additionally, the composition in alternative embodiment includes a synergistic antioxidant and further incorporates zinc gluconate in certain embodiments. The method for topical application of the composition includes drops, a rinse, cream, gel or saturated wick.
机译:L-抗坏血酸以约2%至约25%wt / vol的浓度局部施用于人外耳道和鼻膜以减轻炎症和感染症状并预防性传播疾病的组合物,在具有药学上可接受的液体载体的水溶液中,分别在约4.0至2.0pH的酸性范围内或pH水平下。在替代的示例性实施方案中,液体载体是纯蒸馏水或标准的0.9%生理盐水,其pH值在预定的组合物中调节以获得所需的治疗效果。在替代的示例性实施方案中,液体载体是纯蒸馏水或标准的0.9%生理盐水,这取决于本发明中活性成分对宿主组织的优选吸收程度和生物利用度。这可能包括氯化钠作为首选的海盐-经分析,该盐包含99%的氯化钠和钙,镁,硫酸盐,铁和铜矿物质。另外,在替代实施方案中,组合物包括协同抗氧化剂,并且在某些实施方案中进一步掺入葡萄糖酸锌。局部施用组合物的方法包括滴剂,漂洗剂,乳膏剂,凝胶剂或饱和芯。

著录项

  • 公开/公告号US2010247694A1

    专利类型

  • 公开/公告日2010-09-30

    原文格式PDF

  • 申请/专利权人 JOSEPH DI BARTOLOMEO;

    申请/专利号US20100814259

  • 发明设计人 JOSEPH DI BARTOLOMEO;

    申请日2010-06-11

  • 分类号A61K31/375;A61K31/355;A61K36;A61P29;A61P31;A61P27/16;

  • 国家 US

  • 入库时间 2022-08-21 18:53:55

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