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QUANTITATIVE SINGLE IMAGE-BASED MAGNETIZATION TRANSFER WEIGHTED IMAGING USING AN INTER-SUBJECT NORMALIZATION REFERENCE WITHIN THE IMAGE
QUANTITATIVE SINGLE IMAGE-BASED MAGNETIZATION TRANSFER WEIGHTED IMAGING USING AN INTER-SUBJECT NORMALIZATION REFERENCE WITHIN THE IMAGE
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机译:使用图像中的对象间归一化参考,基于量化的基于单图像的磁化传递加权成像
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摘要
Disclosed is a system and method for generating quantitative imagery of demyelination in the spinal cord. The method includes acquiring a magnetization transfer weighted (MTw) MR image of the spinal column, identifying a reference region of interest within the image corresponding to cerebrospinal fluid (CSF), averaging the signal intensity corresponding to the reference region of interest, and computing a ratio, on a voxel-by-voxel basis, of the signal intensity of each voxel by the averaged reference signal intensity. In doing so, normalized MTw images are obtained such that detrimental artifacts such as motion-induced errors, coil loading, and RF coil sensitivity variations are obviated.
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