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Adjuvant for Transdermal or Transmucosal Administration and Pharmaceutical Preparation Containing the Same
Adjuvant for Transdermal or Transmucosal Administration and Pharmaceutical Preparation Containing the Same
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机译:用于透皮或透粘膜给药的佐剂和含有该佐剂的药物制剂
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摘要
It is intended to provide a low molecular weight adjuvant which can be administered safely without inducing skin irritation or the like by transdermal or transmucosal administration and is for enhancing immunogenicity of an antigen efficiently. It can be achieved by an immunostimulant adjuvant containing at least one substance selected from the group consisting of aliphatic alcohols, free fatty acids and fatty acid derivatives but does not contain a substance represented by the following formula.; ;(In the formula, R3 and R4 may be combined to form a cyclic ring, and R1 and R2 independently represent an alkyl side chain having 1 to 16 carbon atoms.)
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