首页> 外国专利> Double-Stranded Nucleic Acid Molecule Cancer Cell Proliferation Inhibitor and Pharmaceutical Agent Suitable for Prevention or Treatment of Uterine Cancer, Breast Cancer, and Bladder Cancer

Double-Stranded Nucleic Acid Molecule Cancer Cell Proliferation Inhibitor and Pharmaceutical Agent Suitable for Prevention or Treatment of Uterine Cancer, Breast Cancer, and Bladder Cancer

机译:适用于预防或治疗子宫癌,乳腺癌和膀胱癌的双链核酸分子癌细胞增殖抑制剂和药剂

摘要

A double-stranded nucleic acid molecule for suppressing the expression of at least one of COX7RP and Efp genes which includes (a) a sense strand which includes a nucleotide sequence corresponding to a target sequence indicated by any one of SEQ ID Nos.: 1 to 38 and (b) an antisense strand which includes a nucleotide sequence complementary to that of the sense strand specified in (a); a cancer cell proliferation inhibitor with the double-stranded nucleic acid molecule and against at least one of uterine, breast and bladder cancer cells; and a pharmaceutical agent with the cancer cell proliferation inhibitor and against at least one of uterine, breast and bladder cancers.
机译:一种用于抑制COX7RP和Efp基因中至少一个的表达的双链核酸分子,其包括(a)有义链,该有义链包括对应于SEQ ID Nos.1至1中任何一个所示的靶序列的核苷酸序列。 38和(b)反义链,其包含与(a)中指定的有义链的核苷酸序列互补的核苷酸序列;一种具有双链核酸分子并针对子宫,乳腺癌和膀胱癌细胞中的至少一种的癌细胞增殖抑制剂;以及具有癌细胞增殖抑制剂并且针对子宫癌,乳腺癌和膀胱癌中的至少一种的药剂。

著录项

  • 公开/公告号US2010173405A1

    专利类型

  • 公开/公告日2010-07-08

    原文格式PDF

  • 申请/专利权人 SATOSHI INOUE;KAZUHIRO IKEDA;

    申请/专利号US20090642979

  • 发明设计人 SATOSHI INOUE;KAZUHIRO IKEDA;

    申请日2009-12-21

  • 分类号C12N15/63;C07H21/04;

  • 国家 US

  • 入库时间 2022-08-21 18:51:12

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