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Vertebrate embryonic pattern-inducing proteins, and uses related thereto
Vertebrate embryonic pattern-inducing proteins, and uses related thereto
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机译:脊椎动物胚胎模式诱导蛋白及其相关用途
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摘要
The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here hedgehog-related genes, comprise morphogenic signals produced by embryonic patterning centers, and are involved in the formation of ordered spatial arrangements of differentiated tissues in vertebrates. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.
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