首页>
外国专利>
Methods and compositions for treating pachyonychia congenita
Methods and compositions for treating pachyonychia congenita
展开▼
机译:治疗先天性肺炎的方法和组合物
展开▼
页面导航
摘要
著录项
相似文献
摘要
A method for treating pachyonychia congenita (PC) by identifying a genetic mutation contributing to PC, preparing a siRNA sequence that inhibits expression of the identified mutation, and administering the siRNA to a cell of a subject afflicted with PC. The siRNA treatment can include silencing of both the mutated and associated wildtype genes for a specific keratin. Specific mutations and inhibitory sequences are identified.
展开▼