Cytogenetically determined prognosis of myeloma

摘要

The invention provides methods and materials for determining a prognosis for myeloma and myeloma-disposed patients. The methods include the use of FISH techniques. The identification of the chromosomal abnormalities t(4;14)(p16;q32), t(14;16)(q32;q23), or 17p13 deletion (p53) in plasma cells from a patient indicates a poor prognosis.