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Compositions and methods useful for treating circulatory and hypovolemic shock
Compositions and methods useful for treating circulatory and hypovolemic shock
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机译:用于治疗循环性和低血容量性休克的组合物和方法
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摘要
Polypeptides, compositions, and methods for treating shock are described. A isolated polypeptide, Deltorphin-E, can be administered without concomitant fluid resuscitation, before, concurrently with, or after the onset of shock or the occurrence of an event that creates a risk of shock. Deltorphin-E can be administered in accordance with the method as part of a preconditioning strategy, which reduces the extent of ischemic injury. Deltorphin-E can be used in preparation for planned ischemia or in a prophylactic manner in anticipation of further ischemic events.
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