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Methods and compositions for blood pool identification, drug distribution quantification and drug release verification
Methods and compositions for blood pool identification, drug distribution quantification and drug release verification
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机译:用于血池鉴定,药物分布定量和药物释放验证的方法和组合物
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摘要
Methods and compositions useful for detecting an in vivo blood pool, monitoring the distribution of a compound of interest to a desired site in an organism by magnetic resonance imaging, monitoring the accumulation of a compound of interest at a desired site in vivo by magnetic resonance imaging, and monitoring the release of liposomal contents to an external stimulus at a desired site in vivo by magnetic resonance imaging are disclosed. Some compositions comprise envirosensitive or non-sensitive liposomes. Contrast agents, such as manganese-based compounds, are also disclosed.
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