首页> 外国专利> 2 - 3 - (2,2 - difluoro - benzo 1,3 dioxol - 5 - ilamino) - 5 - (2,6-dimethyl pyridin-4-yl) 1,2,4 triazol yl - 1 - N - Ethyl acetamide and analogs thereof, Pharmaceutical compositions containing them, and process of Preparation use of the same in psychotic Disorders and / or Diseases with intellectual difficulties.

2 - 3 - (2,2 - difluoro - benzo 1,3 dioxol - 5 - ilamino) - 5 - (2,6-dimethyl pyridin-4-yl) 1,2,4 triazol yl - 1 - N - Ethyl acetamide and analogs thereof, Pharmaceutical compositions containing them, and process of Preparation use of the same in psychotic Disorders and / or Diseases with intellectual difficulties.

机译:2-[3-(2,2-二氟-苯并[1,3]二恶唑-5-氨基]-5-(2,6-二甲基吡啶-4-基)] [1,2,4三唑基]- 1-N-乙乙酰胺及其类似物,包含它们的药物组合物及其在精神病和/或智力障碍疾病中的制备方法。

摘要

Processes for preparing them and Pharmaceutical compositions containing them and their use in therapy are positive allosteric modulators of nicotinic acetylcholine receptors that have the capacity to increase the efficacy of agonists of nicotinic receptors.Claim 1: a compound of the formula (1) or a Salt or hydrate acceptable for pharmaceutical use, or a solvate thereof.
机译:制备它们的方法和包含它们的药物组合物及其在治疗中的用途是烟碱乙酰胆碱受体的正变构调节剂,其具有增加烟碱受体激动剂功效的能力。权利要求1:式(1)的化合物或盐或药学上可接受的水合物或其溶剂化物。

著录项

  • 公开/公告号AR068919A1

    专利类型

  • 公开/公告日2009-12-16

    原文格式PDF

  • 申请/专利权人 JANSSEN PHARMACEUTICA N.V.;

    申请/专利号AR2008P104545

  • 发明设计人

    申请日2008-10-17

  • 分类号C07D405/14;C07D401/14;A61K31/357;A61K31/4196;A61K31/4427;A61P25/00;A61P25/18;A61P25/22;A61P25/24;A61P25/28;

  • 国家 AR

  • 入库时间 2022-08-21 18:47:33

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