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Derived from 3 - phenyl propanoic acid activators of PPAR type Receptors, and Use thereof in cosmetic or Pharmaceutical compositions

机译:衍生自PPAR型受体的3-苯基丙酸活化剂,及其在化妆品或药物组合物中的用途

摘要

Compounds of the formula (1), as well as their method of preparation, and their use in Pharmaceutical compositions intended for use in human or Veterinary Medicine (Dermatology, as well as in the field of cardiovascular diseases, immune diseases and Or Diseases related to Lipid Metabolism), or also in cosmetic compositions.Claim 1: Compound characterized in that responds to the General formula (1): in which ru00b9 represents a radical hydroxyl or alkoxy radical; radical Ru00b2 represents Hydrogen, alkyl, cycloalkyl Radicals, a radical aralquilo eventually replaced, or a radical Polyether Ru00b3; a represents Hydrogen, halogen,A radical alkyl or alkoxy radical; radical ru2074 represents an alkyl, aryl radical, eventually replaced, or a radical aralquilo eventually replaced; X represents an oxygen Atom or radical chu2082; and represents an oxygen Atom, a radical nru2075 osou2082, a radical, or CoNru2075co or nru2075sou2082; ru2075 represents a hydrogen Atom or an alkyl radical, as well as their salts with a pharmaceutically acceptable acid or base, their pharmaceutically acceptable Solvents, and their carbohydrate.
机译:式(1)化合物及其制备方法,以及它们在打算用于人或兽药(皮肤病)以及心血管疾病,免疫疾病和/或相关疾病的药物组合物中的用途权利要求1:一种化合物,其特征在于响应通式(1):其中r b9b代表羟基或烷氧基。基团R u00b2表示氢,烷基,环烷基基团,最终被取代的芳基基团或基团聚醚R u00b3; a代表氢,卤素,烷基或烷氧基。 r u2074代表最终被取代的烷基,芳基或最终被取代的芳基基; X代表氧原子或自由基ch u2082;并代表氧原子,基团,基团或CoNr u2075co或nr u2075so u2082; r 2075表示氢原子或烷基,以及它们与可药用的酸或碱的盐,其可药用的溶剂和其碳水化合物。

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