N- (HETEROCYCLYL) BENZENE OR PYRIDINE SULFONAMIDES AS ANTITROMBOSE AGENTS AND ANTICOAGULANTS

摘要

The invention relates to compounds of the formula wherein W may represent - (CH 2) 2 -, - (CH 2) -C C- or -CH 2 -CH = CH- group, R 2 may in particular denote a piperidinyl group, , 2,3,6-tetrahydropyridinyl group, optionally substituted hexahydro-1 (OH) -azepinyl group, piperazinyl group, optionally substituted or morpholinyl group, R 3 may denote a -COOR 1 group , A may in particular be a phenyl group, optionally substituted, a heterocycle or a cyclopentyl group, and B may in particular denote a pyridyl group, an aminopyrazinyl group, and a pyrimidinyl group optionally substituted by an amino group, a piperidinyl or aminopyridinyl group optionally substituted on pyridine by a (C 1 -C 4) alkyl or a (C 1 -C 4) alkoxy group, the amino group being optionally substituted by (C 1 -C 4) C1-C4) alkyl group. The invention also relates to the preparation of these compounds and to their therapeutic use.