首页> 外国专利> Compound (e) - N - (5 - (e) - 3 - Fluoro - 6H - dibenzo B, E oxepin - 11 - ilidenmethy) - 1 - ((R) - 1 - methyl - 2 - morphine - 4 - Il - ethyl) - 1, 3 - dihydro - benzimidazol - 2 - iliden) - urea, its salts, opposite non - sterol receivers; pharmacological synthesis; and its use in the treatment of congestive heart failure and ischemic heart disease Florpatia with diabetes

Compound (e) - N - (5 - (e) - 3 - Fluoro - 6H - dibenzo B, E oxepin - 11 - ilidenmethy) - 1 - ((R) - 1 - methyl - 2 - morphine - 4 - Il - ethyl) - 1, 3 - dihydro - benzimidazol - 2 - iliden) - urea, its salts, opposite non - sterol receivers; pharmacological synthesis; and its use in the treatment of congestive heart failure and ischemic heart disease Florpatia with diabetes

机译:化合物(e)-N-(5-[(e)-3-氟-6H-二苯并[B,E]氧杂环丁烷-11-苯甲基)-1-((R)-1-甲基-2-吗啡-4 -II-乙基)-1,3-二氢-苯并咪唑-2-Iilden)-脲,其盐,与非甾醇受体相对;药理合成及其在治疗充血性心力衰竭和缺血性心脏病Flotapatia合并糖尿病中的应用

摘要

Compounds derived from 5 - [(e) dibenzo [B, e] oxepin - 11 (6H) - ilidenmetil] - 1,3 dihydro - - 2 - - 2H benzimidazole iMine,Mineralocorticoid Receptor Antagonists, Pharmaceutical Composition and use in the treatment of Physiological disorders, such as congestive heart failure,Diabetic neuropathy or chronic kidney disease.
机译:衍生自5-[(e)二苯并[B,e] oxepin-11(6H)-ilidenmetil]-1,3二氢--2--2H苯并咪唑iMine,盐皮质激素受体拮抗剂,药物组合物的化合物以及用于治疗生理疾病,例如充血性心力衰竭,糖尿病性神经病或慢性肾脏疾病。

著录项

  • 公开/公告号CL2008003600A1

    专利类型

  • 公开/公告日2010-02-19

    原文格式PDF

  • 申请/专利权人 ELI LILLY AND COMPANY;

    申请/专利号CL20080003600

  • 申请日2008-12-03

  • 分类号A61K31/4184;A61P5/42;C07D207/14;C07D233/66;C07D313/12;C07D405/06;C07D405/14;C07D498/04;

  • 国家 CL

  • 入库时间 2022-08-21 18:47:13

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