18 - 19 nor androst - methyl - 4 - 17 espiroeteres (17 - 18 - 19 20 - nor - methyl - 4 - 3 - espirox ones) as well as Preparations Containing Pharmaceuticals

摘要

1. - 18-methyl-15 Di,16 di-methyl-19-nor-20-helix-4-en-3-onas general formula I-I en dondez is an oxygen atom, two hydrogen atoms, a group = nor or nnhso2r, where R is a hydrogen atom, or a linear or separator group, 1-4 or 3-4 carbon atoms, and R4 is a hydrogen atom, A halogen atom or a trifluoroethylene group, and R6 and / or R7 may be in a or a position,R6 and R7 are independent,Hydrogen atom or linear or separable chain coke group, 1 to 4, or 3 to 4 carbon atoms, or 2 to 4 linear or separable chain groups, or 3 to 4 carbon atoms, or 3 to 4 carbon atoms, or 3 to 5 carbon atoms saturated cyclododecane group, or both have a methylene group or two bonds. 2. - 18-methyl-15 Di,16-methyl-19-nor-20-helix-4-en-3-onas, general formula I, is characterized by that z is an oxygen atom. 3. - 18-methyl-15 Di,16-methyl-19-nor-20-helix-4-en-3-onas of the general form I is characterized by hydrogen atom, methyl group or chlorine atom. 4. - 18-methyl-15,16-methyl-19-nor-20-helix-4-en-3-onas, general formula I, characterized by R6 and R7 being a 5A, 6a or 5B group,Or add a link. 5. - 18-methyl-15 Di,16-methyl-19-nor-20-helix-4-en-3-onas, general formula I, characterized by R7 being a-o-methyl -,Ethyl.Propylene or the residue of etenero or a-o-cyclopapile.