COMPOUNDS 4-PIPERIDINYLMOLEVINS (OPTIONS), PHARMACEUTICAL COMPOSITION ON THEIR BASIS (OPTIONS) AND METHOD FOR TREATING DISEASES MEDIATED BY SOLVABLE EPOXYDROHYDROLOSE OF THE DISEASES MEDIATED BY SOLVABLE EPOXYDROHYDROLASO TREATMENT, TREATMENT OF THE DISTRIBUTION MEDIATED WITH SOLVABLE EPOXYDROHYDROLOSE OF THE DISEASE MEDIATED BY SOLVABLE EPOXYDROHYDROLA AROUND AND MEANS OF THE PROTECTION OF THE DISTRIBUTION, MEDIATED BY THE MEANS OF THE DISPOSAL OF THE DISEASE

摘要

Urea compounds from a stereoisomer or a pharmaceutically acceptable salt and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compound and compositions, and methods for treating patients using these compounds and compositions are described. The compounds, compositions and methods are used to treat a variety of sEH-mediated diseases, including hypertensive, cardiovascular, inflammatory, pulmonary and diabetes-related diseases.