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BIOMATERIALS FOR PREVENTING POST-SURGICAL ADHESIONS COMPRISED OF HYALURONIC ACID DERIVATIVES
BIOMATERIALS FOR PREVENTING POST-SURGICAL ADHESIONS COMPRISED OF HYALURONIC ACID DERIVATIVES
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机译:预防由透明质酸衍生物组成的术后粘连的生物材料
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摘要
A composite biomaterial (I) for preventing surgical tissue adhesions comprises at least one hyaluronic acid (HA) deriv. selected from (a) benzyl esters of HA in which 75-100% of the COOH gps. of HA are esterified with benzyl and up to 25% are esterified with 10-20C alkyl, provided that at least 80% of the COOH gps. are esterified; and (b) self-crosslinked HA derivs., in which 0.5-20% of the COOH gps. of HA are crosslinked to OH gps. of the same or different HA molecules. Also claimed is the use of (I) for preventing surgical adhesions and a method for preventing tissue adhesions using (I).
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