3-(4-AMINO-1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)- PIPERIDINE- 2, 6-DIONE FOR USE IN A MEDICAMENT FOR TREATING AND MANAGING MYELODYSPLASTIC SYNDROMES

摘要

Methods of treating, preventing and/or managing myclodysplastic syndromes are disclosed. Specific methods encompass the administration of an immunomodulatory compound, or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate, or prodrug thereof, alone or in combination with a second active ingredient, and/or the transplantation of blood or cells. Specific second active ingredients are capable of affecting or blood cell production. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.