METHODS OF TREATING A SECONDARY BONE TUMOR WITH ANTI-PDGFRALPHA ANTIBODIES

摘要

The invention provides methods of treating bone cancer, particularly metastatic bone cancer, by administering an IGF-IR antagonist and/or a PDGFRα antagonist. The invention also provides antibodies that bind to human PDGFRα, and a method of treating a mammal with a neoplastic disease using the antibody alone or in combination with other agents.