A NANOPARTICULATE EXOGENOUS PROTEIN-FREE MICRONUTRIENT ADDED PULMONARY SURFACTANT COMPOSITION FOR NEONATAL RESPIRATORY DISTRESS SYNDROME AND A PROCESS FOR PREPARING THE SAME.

摘要

This invention relates to a nanoparticulate exogenous micronutrient added protein-free surface composition for use in treating Neonatal Respiratory Distress Syndrome (NRDS) and a process for preparing the same. The composition contains atleast one phospholipid surfactant and a natural oil selected from clove or eucalyptus oil and their derivatives, micronutrients selected from ascorbic acid and its derivatives and soluble calcium salts. This composition is cost effective, does not have the side -effects normally seen when animal derived protein containing surfactants are used and acts also as a delivery agent for essential micronutrients for the premature babies lungs.