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IMMUNOGENIC COMPOSITIONS COMPRISING MYCOBACTERIUM TUBERCULOSIS POLYPEPTIDES AND FUSIONS THEREOF.

机译：包含结核分支杆菌多肽及其融合的免疫原性组合物。

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摘要

The present invention relates to compositions and fusion proteins containing at least two Mycobacterium sp. antigens, and polynucleotides encoding such compositions and fusion proteins. The invention also relates to methods for their use in the treatment, prevention and/or diagnosis of tuberculosis infection.

机译：本发明涉及包含至少两个分枝杆菌属物种的组合物和融合蛋白。抗原，以及编码此类组合物和融合蛋白的多核苷酸。本发明还涉及其用于治疗，预防和/或诊断结核感染的方法。

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公开/公告号MX2009010800A

专利类型
公开/公告日2010-01-29

原文格式PDF
申请/专利权人 INFECTIOUS DISEASE RESEARCH INSTITUTE (IDRI);
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申请/专利号MX20090010800
发明设计人 REED STEVEN G.;COLER RHEA N.;IRETON GREGORY C.;
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申请日2008-04-04
分类号A61K39/04;A61P31/06;C07K14/35;G01N33/569;
国家 MX
入库时间 2022-08-21 18:45:46

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3. A novel recombinant DNA vaccine encoding Mycobacterium tuberculosis ESAT-6 and FL protects against Mycobacterium tuberculosis challenge in mice [J] . Qingtao Jianga, Jing Zhang, Xia Chen, 生物医学研究杂志：英文版 . 2013,第005期

4. Immunogenicity and Protective Efficacy Conferred by a Novel Recombinant Mycobacterium bovis Bacillus Calmette-Guérin Strain Expressing Interleukin-12p70 of Human Cytokine and Ag85A of Mycobacterium tuberculosis Fusion Protein [J] . DengY.H., HeH.Y., ZhangF.J. Scandinavian journal of immunology. . 2013,第6期

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