首页> 外国专利> Cycloalkene derivatives for supressing the effects of endotoxins

Cycloalkene derivatives for supressing the effects of endotoxins

机译:环烯烃衍生物抑制内毒素的作用

摘要

Disclosed is a compound of formula (I), or a pharmacologically acceptable salt thereof, wherein X and Y are either substituents as defined in the specification or together form a ring, l and m are each 0-3 and their sum is 1-3, and wherein the other substituents are as described in the specification. Also disclosed is the use of the compound for suppressing intracellular signal transduction or cell activation induced by endotoxin, and for treating diseases associated with this transduction or activation, such as sepsis.
机译:公开了式(I)的化合物或其药理学上可接受的盐,其中X和Y为说明书中定义的取代基或一起形成环,l和m分别为0-3且其总和为1-3 ,其中其他取代基如说明书中所述。还公开了该化合物用于抑制由内毒素诱导的细胞内信号转导或细胞活化,以及用于治疗与这种转导或活化相关的疾病如败血症的用途。

著录项

  • 公开/公告号NZ567269A

    专利类型

  • 公开/公告日2010-06-25

    原文格式PDF

  • 申请/专利权人 DAIICHI SANKYO COMPANY LIMITED;

    申请/专利号NZ20060567269

  • 申请日2006-09-13

  • 分类号C07C311/14;A61K31/215;A61K31/336;A61K31/343;A61K31/357;A61K31/385;A61K31/39;A61K31/40;A61K31/4025;A61K31/443;A61K31/5375;A61P43;C07D207/50;C07D303/36;C07D307/94;C07D311/96;C07D317/72;C07D319/08;C07D327/04;C07D339/06;C07D339/08;C07D405/12;C07D413/12;C07D493/10;

  • 国家 NZ

  • 入库时间 2022-08-21 18:45:25

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号