Anti-infective solution comprising a pyrido(3,2,1-IJ)-benzoxadiazine compound (such as marbofloxacin), a stabilizing agent, and a solubilization agenet

摘要

Disclosed is an anti-infection solution, which comprises: (i) 10-30% (w/w) of a compound of the pictured formula, or a pharmaceutically acceptable salt thereof, wherein X is hydrogen, halogen, or hydroxy, R2 is alkyl or cycloalkyl, and R1 is a ring group selected from the list given in the specification, (ii) benzyl alcohol, and (iii) at least one organic acid or an ester thereof, in a pharmaceutically acceptable carrier. Also disclosed is the use of the composition to treat infections in animals.