METHOD FOR ASSESSING PRIMARY REFRACTORINESS IN PATIENTS WITH GIANT B-CELL NON HODGKIN LYMPHOMA OF LOW RISK GROUP

摘要

A method for assessing the primary refractoriness in the patients with giant B-cell non Hodgkin lymphoma of low risk group comprises the assessment of the international prognostic index (age of the patient, lactate dehydrogenase activity, the general state of the patient, the stage of the disease, and the number of extranodal lesions). In addition, the expression of PKCII is assayed immunohistochemically. The high expression of PKCII in more than 80 % of cells is indicative of the unfavorable prognosis.