SMALL ORGANIC MOLECULES REGULATING THE CELL PROLIFERATION.

摘要

A pharmaceutical preparation comprising a compound with a structure of Formula VIII: Formula VIII Where, as valence is allowed, U represents a substituted or unsubstituted aryl or heteroaryl ring fused to the nitrogen containing ring; V represents methylene, 1,1-ethylene or 1,1-propylene; W represents S or O, preferably O; X represents C = O, C = S, or SO2; R3 represents, aryl, heteroaryl, lower alkyl, substituted or unsubstituted lower alkenyl, lower alkynyl, carbocyclyl, carbocyclylalkyl, heterocyclyl, heterocyclylalkyl, aralkyl, or heteroaralkyl; R4 represents, a substituted or unsubstituted aralkyl or lower alkyl, such as a phenethyl, benzyl, or aminoalkyl, etc .; R5 represents, a substituted or unsubstituted aryl, heteroaryl, aralkyl, or heteroaralkyl, including polycyclic or heteroaromatic aromatic groups. or a pharmaceutically acceptable salt thereof.