PLASMINE INHIBITORS OF AUSTRALIAN BROWN SNAKE, PSEUDONAJA TEXTILIS TEXTILIS.

摘要

A substantially pure preparation of a plasmin inhibitor characterized in that this is a competitive single stage plasmin inhibitor and comprises the amino acid sequence ECESTCAA, wherein the plasmin inhibitor has the general formula: ** (See formula) ** where : X is any amino acid; Y is a hydrophobic amino acid; Ã is an aromatic amino acid or histidine; Z is K, R, H, D, E, Q or N; and B is a neutral amino acid, or P, A, G, S, T, V or L, and where X in position 19 is R.