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HOMOLOGOS OF HUMAN TYPE TOLL.

机译:人类型同志商标。

摘要

Isolated nucleic acid molecule comprising a polynucleotide sequence that has at least 95% sequence identity with: (a) a DNA molecule encoding a PRO286 polypeptide having amino acid residues of 27 to 825 of the figure 1 (SEQ ID NO: 3) in which the polypeptide has the ability to induce the activation of NF-κB, or the complement of the DNA molecule; or (b) a DNA molecule that encodes the same mature polypeptide encoded by the Toll-like human protein cDNA in ATCC No. 209386 (DNA42663-1154), in which the polypeptide has the ability to induce the activation of NF-κB, or the complement of the DNA molecule.
机译:分离的核酸分子,其包含与以下分子具有至少95%序列同一性的多核苷酸序列:(a)编码具有图1的27至825个氨基酸残基的PRO286多肽的DNA分子(SEQ ID NO:3),其中多肽具有诱导NF-κB或DNA分子补体激活的能力; (b)编码与ATCC编号209386(DNA42663-1154)中的Toll样人蛋白质cDNA编码的相同成熟多肽相同的DNA分子,其中该多肽具有诱导NF-κB活化的能力,或DNA分子的补体。

著录项

  • 公开/公告号ES2343210T3

    专利类型

  • 公开/公告日2010-07-26

    原文格式PDF

  • 申请/专利权人 GENENTECH INC.;

    申请/专利号ES20070020354T

  • 申请日1998-10-07

  • 分类号C07K1;C12N15/09;A61K38;A61K39/395;A61K45;A61P9/02;C07K14/47;C07K14/705;C07K16/28;C07K16/46;C07K19;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12P21/02;C12P21/08;G01N33/574;G01N33/68;

  • 国家 ES

  • 入库时间 2022-08-21 18:43:03

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