USE OF FIBROBLAST GROWTH FACTORS MUTANTS TO STIMULATE BONE GROWTH

摘要

The present invention provides therapeutic compositions for the prevention and treatment of pathological conditions involving bone and dental tissue. The present invention also provides a method to promote bone repair and/or growth for the treatment of pathological conditions involving bone tissue, for example, osteoporosis, Paget's disease, osteopetrosis, and periodontal disease and fracture rapair, and healing of bone defects by administering FGF-1 to an animal or human in need of said treatment.