Compounds are disclosed that have formula I: where A, B, L1, W, Y, R1, and R3are as defined herein. The com-pounds and pharmaceutical compositions thereof are useful for the preventionand treatment of a variety of conditions in mammalsincluding humans, including by way of non- limiting example, pain, anxiety,depression, inflammation, cognitive disorders,weight and eating disorders, Parkinson's disease, Alzheimer's disease,spasticity, addiction, glaucoma, and others.
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