NEW PROCESS FOR THE PREPARATION OF 1- 5-(3-CHLORO-PHENYL)-ISOOXAZOL-3-YL-ETHANONE AND (R)-1-5-(3-CHLORO-PHENYL)-ISOOXAZOL-3-YL-ETHANOL

摘要

The present invention provides a process for the preparationof the compound 1- [5- (3-chloro-phenyl) -isooxazol-3-yl] - ethanone:Wherein the compound 5- (3-chlorophenyl) -isooxazol-3- carboxylate isreacted with CH3MgX. The present invention also provides a process forthe preparation of (R) -1- [5- ( 3-chloro-phenyl) -isooxazol-3-yl] -ethanol : Wherein 1- [5- (3-chloro-phenyl) -isooxazol-3-yl] -ethanone isreduced to (R) -1- [5- (3-chloro-phenyl) -isooxazol-3-yl] -ethanol.