首页> 外国专利> 3-methyl-2- (3- (2-phenyl-oxazol-4-ylmethoxy)-cyclohexanecarbonyl-amino butyric acid derivatives and related compounds as PPAR modulators for the treatment of type 2 diabetes and atherosclerosis

3-methyl-2- (3- (2-phenyl-oxazol-4-ylmethoxy)-cyclohexanecarbonyl-amino butyric acid derivatives and related compounds as PPAR modulators for the treatment of type 2 diabetes and atherosclerosis

机译:3-甲基-2-(3-(2-苯基-恶唑-4-基甲氧基)-环己烷羰基-氨基丁酸衍生物和相关化合物作为PPAR调节剂,用于治疗2型糖尿病和动脉粥样硬化

摘要

The invention relates to arylcycloalkyl-substituted alkanoic acid derivatives and to their physiologically acceptable salts and physiologically functional derivatives. What is described are compounds of the formula I, in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparation. The compounds are suitable, for example, for the treatment and/or prevention of disorders of the fatty acid metabolism and glucose utilization disorders and also disorders in which insulin resistance is involved.
机译:本发明涉及芳基环烷基取代的链烷酸衍生物及其生理上可接受的盐和生理功能上的衍生物。所描述的是其中定义如上的基团的式I化合物及其生理上可接受的盐和其制备方法。所述化合物适合例如用于治疗和/或预防脂肪酸代谢疾病和葡萄糖利用疾病以及涉及胰岛素抵抗的疾病。

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