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5-phenyl-4-methyl-thiazol-2-yl-amine derivatives as inhibitors of phosphatidylinositol 3 kinase enzymes (pi3) for the treatment of inflammatory airway diseases

机译:5-苯基-4-甲基噻唑-2-基-胺衍生物作为磷脂酰肌醇3激酶(pi3)的抑制剂,用于治疗炎症性气道疾病

摘要

Compounds of formula I, in free or salt form, wherein Ra, Rb, R2, R3, R4 and R5 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by mediated by phosphatidylinositol 3-kinase. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.
机译:游离形式或盐形式的式I化合物,其中Ra,Rb,R2,R3,R4和R5具有说明书中指示的含义,可用于治疗由磷脂酰肌醇3-激酶介导的病症。还描述了包含所述化合物的药物组合物和制备所述化合物的方法。

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