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SCREENING METHOD FOR THERAPEUTIC AGENT FOR TERATOGENESIS CAUSED BY PRENATAL EXPOSURE TO ALCOHOL

机译:酒精经鼻暴露引起的皮肤发生性疾病的治疗剂的筛选方法

摘要

The present invention relates to a screening method for a therapeutic agent for teratogenesis caused by prenatal exposure to alcohol, a diagnostic method and a diagnostic kit. More particularly, the present invention relates to a screening method for a therapeutic agent for treatment of teratogenesis caused by prenatal exposure to alcohol including observing changes in the expression of Bcl-2 and Bax, apoptosis-related protein and increase/decrease in the Bcl-2/Bax ratio in the forebrain, midbrain and hindbrain, a diagnostic method and a diagnostic kit.
机译:本发明涉及对产前暴露于酒精引起的致畸作用的治疗剂的筛选方法,诊断方法和诊断试剂盒。更具体地,本发明涉及用于治疗由产前暴露于酒精引起的致畸的治疗剂的筛选方法,所述方法包括观察Bcl-2和Bax的表达,凋亡相关蛋白的变化以及Bcl-2的增加/减少。前脑,中脑和后脑的2 / Bax比率,诊断方法和诊断套件。

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