首页> 外国专利> COMPOSITIONS OF MODULATORS OF THE WNT/B-CATENIN PATHWAY AND AN N-CINNAMYL-N'-BENZHYDRYL PIPERAZINE AND THEIR USE IN TREATING NEOPLASTIC CONDITIONS INCLUDING MALIGNANT MELANOMA

COMPOSITIONS OF MODULATORS OF THE WNT/B-CATENIN PATHWAY AND AN N-CINNAMYL-N'-BENZHYDRYL PIPERAZINE AND THEIR USE IN TREATING NEOPLASTIC CONDITIONS INCLUDING MALIGNANT MELANOMA

机译:WNT / B-连环蛋白途径调节剂和N-肉桂基-N'-苯并哌嗪的调节剂的组成及其在治疗包括恶性黑色素瘤在内的肿瘤性疾病中的用途

摘要

The present invention is directed to a composition comprising a modulator of the Wnt/ß-catenin pathway or a pharmaceutically acceptable salt thereof and an N-cinnamyl-N'-benzhydryl piperazine or a pharmaceutically acceptable salt thereof. The present invention is also directed to a method of treating a neoplastic condition in a subject by administering the modulator of the Wnt/ß-catenin pathway or a pharmaceutically acceptable salt thereof and an N-cinnamyl-N'-benzhydryl piperazine or a pharmaceutically acceptable salt thereof to the subject under conditions effective to treat a neoplastic disorder.
机译:本发明涉及一种组合物,其包含Wnt /β-连环蛋白途径的调节剂或其药学上可接受的盐和N-肉桂基-N'-苯甲酰基哌嗪或其药学上可接受的盐。本发明还涉及通过给予Wnt /β-连环蛋白途径的调节剂或其药学上可接受的盐和N-肉桂基-N'-苯甲酰基哌嗪或药学上可接受的方法来治疗对象的肿瘤性疾病的方法。在有效治疗赘生性疾病的条件下将其盐给予受试者。

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