首页> 外国专利> NOVEL {4-2-(DIMETHYLAMINO)-1-(1-HYDROXYCYCLOHEXYL)ETHYLPHENOXY}PHOSPHATE OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, A PRODUCTION METHOD THEREFOR AND A PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING CENTRAL NERVOUS SYSTEM DISORDERS CONTA

NOVEL {4-2-(DIMETHYLAMINO)-1-(1-HYDROXYCYCLOHEXYL)ETHYLPHENOXY}PHOSPHATE OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, A PRODUCTION METHOD THEREFOR AND A PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING CENTRAL NERVOUS SYSTEM DISORDERS CONTA

机译:新型{4- [2-(二甲基氨基)-1-(1-羟基环己基)乙基]苯氧基}磷酸盐或其药学上可接受的盐,其制备方法和预防和治疗中央神经系统疾病的药物组合物

摘要

The present invention relates to a novel {4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenoxy}phosphate or a pharmaceutically acceptable salt thereof, a production method therefor and a pharmaceutical composition for preventing and treating central nervous system disorders which contains the same as an active component. The novel {4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenoxy}phosphate or the pharmaceutically acceptable salt thereof according to the present invention can beneficially be used to prevent and treat central nervous system disorders since it exhibits an equivalent biological and pharmacological activity to venlafaxine and salts thereof which are known in the field, it has very little toxicity, and, in particular, it is outstandingly soluble in water as compared with prior-art venlafaxine derivatives.
机译:本发明涉及新型{4- [2-(二甲基氨基)-1-(1-羟基环己基)乙基]苯氧基}磷酸酯或其药学上可接受的盐,其制备方法和用于预防和治疗中枢神经的药物组合物。包含与活性成分相同的系统疾病。根据本发明的新型{4- [2-(二甲基氨基)-1-(1-羟基环己基)乙基]苯氧基}磷酸酯或其药学上可接受的盐可有益地用于预防和治疗中枢神经系统疾病。与本领域已知的文拉法辛及其盐具有同等的生物学和药理活性,其毒性很小,特别是与现有技术的文拉法辛衍生物相比,其在水中的溶解性极好。

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