A TUMOUR SUPPRESSOR PROTEIN, CASPASE-2

摘要

Methods of diagnosis, prognosis and predisposition assessment of cancer are described comprising detecting, in a suitable body sample from a subject, the presence or absence of at least one non¬ functional allele of caspase-2 gene or, otherwise, a lack or reduction of caspase-2 gene expression. Also disclosed is a method and agent for treating or preventing cancer in a subject.