D-DIMER, TROPONIN, NT-PROBNP FOR PULMONARY EMBOLISM

摘要

The present invention relates to a method of diagnosing acute PE in a subject suspected to suffer from acute PE comprising a) determining the amount of fibrin-fibrinogen degradation products, in particular D-dimer in a sample of the subject; b) determining the amount of a natriuretic peptide in a sample of the subject; c) determining the amount of a cardiac troponin in a sample of the subject; d) comparing the amounts determined in steps a) to c) to reference amounts, thereby establishing the said diagnosis. Comprised are also a method of deciding on a therapy of a subject diagnosed with PE and a method of monitoring the therapy. The present invention also encompasses devices and kits for carrying out the aforementioned methods.