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DETECTION OF BIOCHEMICAL INTERACTIONS ON A BIOSENSOR USING TUNABLE FILTERS AND TUNABLE LASERS

机译:使用可调滤光片和可调激光检测生物传感器上的生物化学相互作用

摘要

An apparatus and method for detection of peak wavelength values of colorimetric resonant optical biosensors using tunable filters and tunable lasers is provided. Biomolecular interactions may be detected on a biosensor by directing collimated white light towards a surface of the biosensor. Molecular binding on the surface of the biosensor is indicated by a shift in the peak wavelength value of reflected or transmitted light from the biosensor, while an increase in the wavelength corresponds to an increase in molecular absorption. A tunable laser light source may generate the collimated white light and a tunable filter may receive the reflected or transmitted light and pass the light to a photodiode sensor. The photodiode sensor then quantifies an amount of the light reflected or transmitted through the tunable filter as a function of the tuning voltage of the tunable filter.
机译:提供了一种使用可调滤光器和可调激光器来检测比色共振光学生物传感器的峰值波长值的装置和方法。通过将准直的白光导向生物传感器的表面,可以在生物传感器上检测生物分子的相互作用。来自生物传感器的反射或透射光的峰值波长值的偏移指示了生物传感器表面上的分子结合,而波长的增加对应于分子吸收的增加。可调激光光源可以产生准直的白光,而可调滤光器可以接收反射或透射的光,然后将其传递给光电二极管传感器。然后,光电二极管传感器根据可调滤波器的调谐电压来量化通过可调滤波器反射或透射的光的量。

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