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HIGHLY WATER PERMEABLE HOLLOW FIBER MEMBRANE-TYPE BLOOD PURIFIER AND PROCESS FOR PRODUCING THE SAME

机译:高透水率的中空纤维膜式血液净化器及其生产工艺

摘要

The present invention relates to a highly water-permeable hollow fiber membrane type blood purifier which comprises hydrophobic polymer hollow fiber membranes each containing a hydrophilic polymer, wherein the hollow fiber membrane has a hydrophilic polymer content of 25 to 50 mass % and a ratio of hole areas of 8 to 25% at its outer surface, and has a thickness non-uniformity degree of 0.6 or more, a thickness of 10 to 60 µm and a burst pressure of 0.5 to 2 MPa, and which is characterized in that the blood purifier has a water permeability of 150 to 2,000 ml/m2/hr/mmHg, and in that said blood purifier is exposed to radioactive rays on conditions that the oxygen concentration of an ambient atmosphere around the hollow fiber membranes is from 0.001% inclusive to 0.1% inclusive, and that the moisture content of the hollow fiber membrane to its weight is from 0.2 mass % inclusive to 7 mass % inclusive. The present invention also relates to a process for manufacturing the same blood purifier.
机译:高透水性的中空纤维膜型血液净化器技术领域本发明涉及一种高疏水性的中空纤维膜型血液净化器,其包括各自含有亲水性聚合物的疏水性聚合物中空纤维膜,其中,所述中空纤维膜的亲水性聚合物含量为25〜50质量%,且空孔率高。 <B>特征在于,在其外表面的面积为8〜25%的区域,厚度不均匀度为0.6以上,厚度为10〜60μm,破裂压力为0.5〜2MPa。 血液净化器的水渗透率为150到2,000 ml / m 2 / hr / mmHg,并且该血液净化器在一定的氧气浓度下暴露于放射线中空纤维膜周围的周围气氛为0.001%以上至0.1%以下,并且中空纤维膜的水分含量相对于其重量为0.2质量%以上至7质量%以下。本发明还涉及用于制造相同的血液净化器的方法。

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