METHOD FOR DETECTING AUTOIMMUNE ANTIBODIES AGAINST TSH RECEPTORS AND NOVEL TSH-RECEPTOR CHIMAERAS

摘要

The invention relates to a method for identifying autoimmune antibodies against TSH receptors with the aid of TSH receptor chimaeras, which, preferably, contain chimaeras which are embodied only in the form of the modified extracellular fraction of a TSH savage-type receptor and are modified by highly immunogenic peptide groups or by detection of suitable enzymes, wherein the inventive determining method makes it possible to easily detecting stimulating, blocking and neutral autoimmune antibodies.