METHOD FOR CHECKING AND QUANTIFYING PROTEIN-LIGAND INTERACTION BY COMBINING A CROSSLINKING METHOD AND ACCELERATOR MASS SPECTROSCOPY

摘要

The present invention provides a novel method for quantifying the production of a protein-ligand composite. Further, the present invention provides a method for checking and quantifying in vitro and in vivo protein-DNA interaction by combining a crosslinking method and accelerator mass spectroscopy. Further, the present invention provides a method for defining a nucleotide excision repair (NER) pathway.