PPAR-Γ-EXPRESSION-ENHANCING AGENT, ADIPONECTIN-PRODUCTION-ENHANCING AGENT, UCP-ACTIVATING AGENT, AND PHARMACEUTICAL PREPARATION, FOOD OR BEVERAGE COMPRISING ANY ONE OF THE AGENTS

摘要

Disclosed are: a PPAR-γ-expression-enhancing agent which comprises procyanidin B2 as an active ingredient and has an activity of enhancing the expression of PPAR-γ; an adiponectin-production-promoting agent which comprises procyanidin B2 as an active ingredient and has an activity of promoting the production of adiponectin; an UCP-activating agent which comprises procyanidin B2 as an active ingredient and has an activity of enhancing the expression of UCP; an anti-diabetes agent, an anti-obesity agent, an agent for reducing the accumulation of a visceral fat or an agent for inhibiting the accumulation of a visceral fat, which comprises any one of the PPAR-γ-expression-enhancing agent, the adiponectin-production-promoting agent and the UCP-activating agent; and a food or beverage comprising any one of the PPAR-γ-expression-enhancing agent, the adiponectin-production-promoting agent and the UCP-activating agent. It becomes possible to provide a pharmaceutical preparation, a food or a beverage which does not cause any adverse side effect, is harmless for a human body, and is expected to have an effect of enhancing the expression of PPAR-γ, an effect of promoting the production of adiponectin, an effect of enhancing the expression of UCP, an effect of ameliorating obesity, diabetes or the like which is induced by the effect of enhancing the expression of PPAR-γ, the effect of promoting the production of adiponectin or the effect of enhancing the expression of UCP, or the like.